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; Yamada, T. Embolic Infarction As already stated, this is the commonest cause of stroke. 29,62 The similarities of the clinical phenotype in two families with different genetic background but the same S252L-ADNFLE mutation strongly suggest that the associated neurologic features are mutation specific rather than caused by modifying genes or environmental factors (Fig.erythema, erosion, ulceration, pain, and discomfort) are the final common pathway for a wide variety of disease processes.
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